Buy Abilify Online

What is Abilify?

Abilify (aripiprazole) is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Abilify is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression). It is also used together with other medications to treat major depressive disorder in adults.

Abilify is also used to treat irritability and symptoms of aggression, mood swings, temper tantrums, and self-injury related to autistic disorder in children who are at least 6 years old.

Abilify may also be used for purposes not listed in this medication guide.

Important information about Abilify

Abilify is not for use in psychotic conditions that are related to dementia. Abilify may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Stop using Abilify and call your doctor at once if you have the following symptoms: fever with stiff muscles and rapid heart rate; uncontrolled muscle movements; symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance.

Before taking Abilify

Abilify is not for use in psychotic conditions that are related to dementia. Abilify may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not take this medicine if you are allergic to aripiprazole.

To make sure you can safely take Abilify, tell your doctor if you have any of these other conditions:

  • liver or kidney disease;
  • heart disease, high blood pressure, heart rhythm problems;

  • high cholesterol or triglycerides (a type of fat in the blood);

  • a history of low white blood cell (WBC) counts;

  • a history of heart attack or stroke;

  • a history of breast cancer;

  • seizures or epilepsy;

  • a personal or family history of diabetes; or

  • trouble swallowing.

The liquid form (oral solution) of Abilify may contain up to 15 grams of sugar per dose. Before taking Abilify oral solution, tell your doctor if you have diabetes. The orally disintegrating tablet form of this medicine may contain over 3 milligrams of phenylalanine per tablet. Before taking Abilify Discmelt, tell your doctor if you have phenylketonuria.

Abilify may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Abilify.

FDA pregnancy category C. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking Abilify, do not stop taking it without your doctor's advice.

Aripiprazole can pass into breast milk and may harm a nursing baby. Do not use Abilify without telling your doctor if you are breast-feeding a baby.

How should I take Abilify?

Take Abilify exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Do not take Abilify for longer than 6 weeks unless your doctor has told you to.

Abilify can be taken with or without food.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

To take aripiprazole orally disintegrating tablets (Abilify Discmelt):

  • Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

  • Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.

  • Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

  • Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Use Abilify regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

Store Abilify tablets at room temperature away from moisture and heat.

Abilify liquid should be stored in the refrigerator and can be used for up to 6 months after opening.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, agitation, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), trouble breathing, or fainting.

What should I avoid while taking Abilify?

Abilify may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Drinking alcohol can increase certain side effects of Abilify. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Abilify.

Abilify side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Abilify: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Abilify and call your doctor at once if you have a serious side effect such as:

  • fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;

  • jerky muscle movements you cannot control;

  • sudden numbness or weakness, headache, confusion, or problems with vision, speech, or balance;

  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;

  • increased thirst or urination, loss of appetite, fruity breath odor, drowsiness, dry skin, nausea, and vomiting;

  • seizure (convulsions);

  • thoughts of hurting yourself;

  • feeling like you might pass out;

  • jaundice (yellowing of your skin or eyes); or

  • urinating less than usual or not at all.

Less serious Abilify side effects may include:

  • choking or trouble swallowing;

  • dizziness, drowsiness, or weakness;

  • constipation, mild stomach upset;

  • headache, anxiety;

  • sleep problems (insomnia); or

  • weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Abilify?

Before you take Abilify, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Abilify.

Tell your doctor about all other medicines you use, especially:

  • a medication to treat high blood pressure or a heart condition;

  • carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin);

  • rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane, Rifater);

  • ketoconazole (Nizoral), itraconazole (Sporanox);

  • quinidine (Quin-G); or

  • fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), or paroxetine (Paxil).

This list is not complete and other drugs may interact with Abilify. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

For the Consumer

Applies to aripiprazole: oral solution, oral tablet, oral tablet disintegrating

Along with its needed effects, aripiprazole (the active ingredient contained in Abilify) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aripiprazole:

More common
  • Difficulty with speaking
  • drooling
  • loss of balance control
  • muscle trembling, jerking, or stiffness
  • restlessness
  • shuffling walk
  • stiffness of the limbs
  • twisting movements of the body
  • uncontrolled movements, especially of the face, neck, and back
Less common
  • Blurred vision
  • dizziness
  • headache
  • inability to move the eyes
  • increased blinking or spasms of the eyelid
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • sticking out the tongue
  • trouble with breathing or swallowing
  • unusual facial expressions
  • Convulsions
  • fast heartbeat
  • high fever
  • high or low blood pressure
  • increased sweating
  • lip smacking or puckering
  • loss of bladder control
  • muscle spasm or jerking of all extremities
  • puffing of the cheeks
  • rapid or worm-like movements of the tongue
  • severe muscle stiffness
  • sudden loss of consciousness
  • tiredness
  • uncontrolled chewing movements
  • uncontrolled movements of the arms and legs
  • unusually pale skin
Incidence not known
  • Hives or welts
  • itching skin
  • itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • redness of the skin
  • shortness of breath
  • skin rash
  • tightness in the chest
  • unusual tiredness or weakness
  • wheezing

Get emergency help immediately if any of the following symptoms of overdose occur while taking aripiprazole:

Symptoms of overdose
  • Bigger, dilated, or enlarged pupils (black part of the eye)
  • diarrhea
  • fast, pounding, or irregular heartbeat or pulse
  • increased sensitivity of the eyes to light
  • lack or loss of strength
  • nausea
  • sleepiness or unusual drowsiness
  • vomiting

Some side effects of aripiprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Acid or sour stomach
  • anxiety
  • belching
  • blurred vision
  • difficulty having a bowel movement (stool)
  • dry mouth
  • fear
  • fever
  • headache
  • heartburn
  • hyperventilation
  • inability to sit still
  • indigestion
  • irritability
  • lightheadedness
  • need to keep moving
  • nervousness
  • rash
  • runny nose
  • shaking
  • sleeplessness
  • sore throat
  • stomach discomfort, upset, or pain
  • trouble sleeping
  • unable to sleep
  • weight gain
Less common
  • Accidental injury
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • body aches or pain
  • congestion
  • coughing
  • difficulty with moving
  • dryness or soreness of throat
  • hoarseness
  • increased appetite
  • increased salivation
  • joint pain
  • muscle aching or cramping
  • muscle pains or stiffness
  • rapid weight gain
  • sneezing
  • stuffy nose
  • swollen joints
  • tender, swollen glands in the neck
  • tingling of the hands or feet
  • tremor
  • unusual weight gain or loss
  • voice changes

Tags: abilify, price of abilify at costco, cheap canadian drugs abilify, abilify cheapest price, abilify on line, side effects of stopping abilify, abilify no prescription canada, order abilify overnight, buy abilify online without rx, no rx abilify, abilify no prescription usa pharmacy, cheapest abilify price, abilify without insurance, abilify cheap price, abilify overnight shipping cheap, abilify 2.5 mg safe and secure, cheap abilify online, generic abilify, abilify online no prescription, drugs comparable to abilify, abilify on line without prescription, abilify rebate, abilify without a prescription, no perscription abilify online, abilify cost without insurance, buy abilify worldwide, buy abilify online, buy abilify 2mg, abilify 15mg price uk, abilify price without insurance, order abilify canada, abilify 10 mg for cheap, abilify no script, abilify with no rx, abilify 10 mg, abilify weight gain, cost of abilify without insurance, abilify pharmacy assist, how much is abilify without insurance, abilify by mail, buying 2mg abilify, abilify online canadian pharmacy, abilify no prescription in mexico, abilify no prescription river pharmacy, abilify cheap, abilify and india, how much abilify to get high, order abilify without a prescription, no prescription generic abilify cheap, i want to buy cheap abilify, pharmacy assist abilify, abilify 10 mg no prescription, order abilify online, purchase abilify, abilify without antidepressant, abilify sale, abilify reviews, buy abilify, aripiprazole abilify, abilify aripiprazole, abilify mg, abilify buy, abilify online, cost of abilify, cost abilify, abilify cost, price of abilify, abilify price, coupon for abilify, abilify coupon, cheap abilify, order abilify, abilify buy online, abilify order, buy abilify cheap, buy cheap abilify, price abilify, 5 mg abilify, 10 mg abilify, 15 mg abilify, abilify 15 mg, abilify 2 mg, 2 mg abilify, 30 mg abilify, abilify 30 mg, 20 mg abilify, abilify 20 mg, abilify 50 mg, abilify 1 mg, 1 mg abilify, abilify 2.5 mg, 1 mg abilify depression, 1 mg abilify weight gain, 10 mg abilify depression, 10 mg abilify weight gain, 10mg abilify depression, 2 mg of abilify and weight gain, 2.5 mg abilify weight gain, 2mg abilify depression, 2mg abilify, 2mg of abilify and weight gain, 4 mg abilify, 5 mg abilify bipolar, 5 mg abilify children, 5 mg abilify weight gain, 90 mg abilify, abilify + cheapest, abilify 1 mg /ml, abilify 10 mg 28 tablet, abilify 10 mg bipolar, abilify 10 mg color, abilify 10 mg price, abilify 10 mg tablet medicijnen, abilify 10 mg tablet medisch, abilify 10 mg tablet, abilify 10 mg tablets, abilify 10mg cost, abilify 15 mg 28 tablet, abilify 15 mg cost, abilify 15 mg costo, abilify 15 mg tab, abilify 15 mg tablet, abilify 15 mg tabletki, abilify 15 mg tabletta, abilify 15 mg tabletten, abilify 15 mg treatment, abilify 15mg price, abilify 15mg prices, abilify 1mg /ml, abilify 1mg/ml solution, abilify 2 mg tablet, abilify 20 mg cost, abilify 20 mg pill, abilify 20 mg tablet, abilify 2mg tablets, abilify 30 mg 28 tablet, abilify 30 mg fiyat, abilify 30 mg price, abilify 30 mg tablets, abilify 30 mg yan etkileri, abilify 30mg price, abilify 5 mg depression, abilify 5mg cost, abilify 5mg price comparison, abilify 5mg tablets, abilify and zoloft, abilify aripiprazol 10 mg, abilify aripiprazole 10 mg, abilify aripiprazole 15 mg, abilify aripiprazole 5 mg, abilify aripiprazole tablets 2mg, abilify available generic form, abilify buy canada, abilify cheap canada, abilify cheaper, abilify cheapest prices, abilify copay discount, abilify cost australia, abilify cost cigna, abilify cost comparison, abilify cost in canada, abilify cost per pill, abilify cost with insurance, abilify costs without insurance, abilify coupon 2012, abilify coupon card, abilify coupons and discounts, abilify coupons free, abilify coupons from manufacturer, abilify coupons printable, abilify discount card, abilify discount coupons, abilify discount plan, abilify discount program, abilify epocrates online, abilify every other day, abilify for depression, abilify free prescription, abilify free trial, abilify generic alternative, abilify generic canada, abilify generic cost, abilify generic date, abilify generic equivalent, abilify generic price, abilify generic, abilify information, abilify interactions, abilify lawsuit, abilify mg size, abilify no prescription needed, abilify online canada, abilify online cost, abilify online coupon, abilify online pharmacy, abilify online prescription, abilify order canada, abilify pill size, abilify pill, abilify prescription card, abilify prescription cost, abilify prescription coupon, abilify prescription drug, abilify prescription program, abilify prescription, abilify price 2mg, abilify price comparison, abilify price increase, abilify price usa, abilify price with insurance, abilify prices canada, abilify prices us, abilify prices usa, abilify qtc, abilify rxlist, abilify sales 2011, abilify sales force, abilify sales revenue, abilify sales us, abilify tabl 15 mg, abilify tablet size, abilify tablets, abilify vs seroquel, abilify with prozac, abilify withdrawal, abilify without rx, abilify xr, best price abilify 2mg, bms abilify sales, buy 20 mg abilify online, buy 2mg abilify online, buy 5 mg abilify, buy abilify 15 mg, buy abilify 2mg canada, buy abilify 5mg online, buy abilify discount, buy abilify from canada, buy abilify no prescription, buy abilify online canada, buy abilify online no prescription, buy abilify uk, buy generic abilify online, buy generic abilify, can i buy abilify online, can you buy abilify canada, can you buy abilify online, cheap abilify 2mg, cheap abilify no prescription, cheap alternative abilify, cheaper alternative abilify, cheaper alternative to abilify, cheaper substitute abilify, cheaper than abilify, cost 5 mg abilify, cost abilify 10 mg, cost abilify 2mg, cost abilify 30 mg, cost abilify canada, cost abilify insurance, cost abilify no insurance, cost of abilify 10mg, cost of abilify 5mg, discount abilify coupon, discount abilify online, discount abilify, does abilify 15 mg look like, does abilify 20 mg look like, effexor xr 150 mg and abilify 5mg, generic abilify (aripiprazole), generic abilify 2mg, generic abilify 5mg, generic abilify available in canada, generic abilify available us, generic abilify available, generic abilify india, generic abilify prices, get abilify cheaper, get cheap abilify, get discount abilify, help buying abilify, how much does abilify cost in canada, how much does abilify cost with insurance, how much does abilify cost without insurance, is 5 mg of abilify a lot, is 5mg of abilify a lot, is abilify generic yet, mail order abilify, much does 10 mg abilify cost, much does abilify 5 mg cost, much does abilify 5mg cost, much does abilify cost canada, much does abilify cost insurance, much does abilify cost without insurance, no prescription abilify, order abilify no prescription, order abilify online canada, order generic abilify, ordering abilify canada, ordering abilify online, price abilify 10mg, price abilify 15 mg, price abilify 20 mg, price abilify 5mg, price abilify canada, price of abilify 15 mg, price of abilify 5mg, price of abilify without insurance, purchase abilify canada, purchase abilify cheap, purchase abilify online, rx abilify, rxlist abilify drug, take 2mg abilify, there generic abilify canada, there generic equivalent abilify, to buy abilify online, together rx abilify, wean off 2mg abilify, where can i buy abilify cheap, where can i buy abilify cheaper, will generic abilify available, abilify order online, abilify order online

Applies to aripiprazole: intramuscular powder for injection extended release, intramuscular solution, oral solution, oral tablet, oral tablet disintegrating

Nervous system

Nervous system side effects have frequently included agitation (25%), anxiety (20% to 25%), insomnia (20% to 24%), akathisia (10% to 15%), lightheadedness (11%), somnolence (11% to 12%), dizziness (11%), sedation (7%), extrapyramidal syndrome (6%), tremor (3% to 9%), restlessness (5%), increased salivation (3%), nervousness, confusion, and abnormal gait. Twitch, cogwheel rigidity, impaired concentration, dystonia, vasodilation, paresthesia, impotence, extremity tremor, hypesthesia, vertigo, stupor, bradykinesia, apathy, decreased libido, hypersomnia, dyskinesia, ataxia, cerebrovascular accident, hypokinesia, depersonalization, impaired memory, delirium, dysarthria, tardive dyskinesia, tardive akathisia, amnesia, hyperactivity, increased libido, myoclonus, restless leg, neuropathy, dysphoria, hyperkinesia, cerebral ischemia, increased reflexes, akinesia, decreased consciousness, hyperesthesia, and slowed thinking have been reported infrequently. Blunted affect, euphoria, incoordination, hypotonia, buccoglossal syndrome, decreased reflexes, and intracranial hemorrhage have been reported rarely. Seizures have been reported in less than 0.1% to 0.3% of patients. Grand mal seizures have been reported in postmarketing experience.

Tardive dyskinesia involves involuntary, dyskinetic, repetitive movements and may be more common in the elderly, especially elderly women, receiving antipsychotics, such as aripiprazole. The exact etiology for the development of tardive dyskinesia secondary to treatment with antipsychotics is unknown. However, research has suggested that the chance of developing tardive dyskinesia and the likelihood that it will be irreversible are increased as the total duration of treatment and the total cumulative dose of antipsychotic medication administered to the patient increase. If a patient receiving aripiprazole therapy shows signs and/or symptoms of tardive dyskinesia discontinuation of therapy should be considered; however, this may not be a clinically feasible option for all patients.

The manufacturer reports elderly patients (mean = 84 years old) enrolled in placebo-controlled studies examining the use of aripiprazole for the treatment of dementia-related psychosis showed an increased incidence of cerebrovascular side effects, e.g. stroke and transient ischemia attacks, including fatalities. The incidence of these effects may be dose related.

A dose-response relationship may exist between aripiprazole and somnolence (placebo, 7.7%; 15 mg, 8.7%; 20 mg, 7.5%; 30 mg, 15.3%).

A possible worsening of preexisting agitation with the initiation of aripiprazole therapy has been reported.

Two cases of aripiprazole-induced acute dystonia have been reported. In one case, symptoms resolved following treatment with trihexyphenidyl and in the other case after discontinuation of aripiprazole. Symptoms of dystonia, prolonged abnormal contractions of muscle groups, may occur in susceptible individuals during the first few days of treatment. Dystonic symptoms include: spasm of the neck muscles, sometimes progressing to tightness of the throat, swallowing difficulty, difficulty breathing, and or protrusion of the tongue. While these symptoms can occur at low doses, they occur more frequently and with greater severity with high potency and at higher doses of first generation antipsychotic drugs. An elevated risk of acute dystonia is observed in males and younger age groups.

At least two cases of aripiprazole-induced seizures have been reported. Conditions that lower the seizure threshold, e.g., Alzheimer's dementia, may be more prevalent in a population over 64 years of age.


Gastrointestinal side effects have included nausea (14% to 16%), dyspepsia (15%), constipation (10% to 13%), vomiting (11% to 12%), dry mouth (5%), abdominal discomfort (3%), and salivary hypersecretion (2%). Increased appetite, dysphagia, gastroenteritis, flatulence, tooth caries, gastritis, gingivitis, gastrointestinal hemorrhage, hemorrhoids, gastroesophageal reflux, periodontal abscess, fecal incontinence, rectal hemorrhage, stomatitis, colitis, tongue edema, cholecystitis, mouth ulcer, oral moniliasis, eructation, fecal impaction, loose stools, abdominal distention, hematochezia, gingival pain, lower abdominal pain, oral pain, retching, fecaloma, tooth fracture, dry lip, and cholelithiasis have been reported infrequently. Esophagitis, hematemesis, intestinal obstruction, gum hemorrhage, peptic ulcer, glossitis, melena, duodenal ulcer, cheilitis, abdominal tenderness, chapped lips, periodontitis, aptyalism, gastrointestinal pain, oral hypoesthesia, inguinal hernia, hyperchlorhydria, irritable bowel syndrome, esophagitis, gingival bleeding, glossodynia, melena, and pancreatitis have been reported rarely.


Dermatologic side effects have frequently included skin ulcer, sweating, and dry skin. Pruritus, vesiculobullous rash, acne, eczema, skin discoloration, alopecia, seborrhea, cellulitis, onychomycosis, and psoriasis have been reported infrequently. Maculopapular rash, exfoliative dermatitis, folliculitis, pustular rash, and urticaria have been reported rarely.


Several cases of aripiprazole-associated neuroleptic malignant syndrome (NMS) have been reported. It should be noted that NMS which is usually characterized by muscle rigidity, dysphagia, tremor, fever, diaphoresis, anxiety, tachycardia, labile blood pressure, and altered consciousness may present in an atypical manner with aripiprazole (the active ingredient contained in Abilify) (i.e., delayed or late onset of typical symptoms such as hyperthermia). One identified potential risk factor for developing NMS is the period during a switch from one antipsychotic treatment to another.

Other side effects have frequently included headache (31% to 32%), asthenia (7% to 8%), accidental injury (5% to 6%), fatigue (6%), pain (3%), fever (2%), peripheral edema (2%), flu syndrome, chest pain, neck pain, pelvic pain, and rigidity in the neck and/or extremities. Face edema, suicide attempt, malaise, chills, photosensitivity, arm rigidity, jaw pain, bloating, tightness (abdomen, back, extremity, head, jaw, neck, and tongue), enlarged abdomen, chest tightness, throat pain, ear pain, tinnitus, otitis media, altered taste, pyrexia, gait disturbance, edema, general physical health deterioration, feeling jittery, decreased mobility, thirst, feeling cold, difficulty in walking, facial pain, sluggishness, candidiasis, and deafness have been reported infrequently. Moniliasis, head heaviness, throat tightness, Mendelson's syndrome, heat stroke, otitis externa, vertigo, localized inflammation, swelling, increased energy, abasia, xerosis, hyperthermia, hypothermia, septic shock, appendicitis, and neuroleptic malignant syndrome have been reported rarely.


Collective data gathered from 17 placebo-controlled clinical studies (n=5106) involving the use of atypical antipsychotic agents, including aripiprazole (the active ingredient contained in Abilify) for the treatment of behavioral disorders in the elderly patient with dementia showed a risk of death 1.6 to 1.7 times greater in the drug- treated patient than in the placebo- treated patient. The average length of duration for the trials was 10 weeks with the cause of death in the majority of cases, though not all, reported as either cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature. Aripiprazole is not approved by the FDA for use in the treatment of behavioral disorders in elderly patients with dementia.

An increased risk of mortality, possibly due to an infection such as pneumonia, has been reported with the use of aripiprazole in the treatment of behavioral disorders in the elderly patient with dementia.

Respiratory side effects have frequently included bronchitis (6%), pharyngitis (4%), rhinitis (4%), coughing (3%), sinusitis, dyspnea, pneumonia, and asthma. Epistaxis, hiccup, laryngitis, and aspiration pneumonia have been reported infrequently. Pulmonary edema, increased sputum, pulmonary embolism, hypoxia, respiratory failure, apnea, dry nasal passages, and hemoptysis have been reported rarely.


Musculoskeletal side effects have frequently included arthralgia (5%), myalgia (4%), pain in extremities (4%), and muscle cramp. Myasthenia, arthrosis, bone pain, arthritis, muscle weakness, spasm, bursitis, and myopathy have been reported infrequently. Rheumatoid arthritis, rhabdomyolysis, tendonitis, and tenosynovitis have been reported rarely.


Ocular side effects have frequently included blurred vision (3%) and conjunctivitis. Dry eye, eye pain, cataract, blepharitis, eye redness, eye irritation, blepharospasm, visual disturbance, eye discharge, increased lacrimation, and eye hemorrhage have been reported infrequently. Diplopia, frequent blinking, ptosis, amblyopia, photophobia, eyelid function disorder, eyelid edema, and oculogyric crisis have been reported rarely.


Hypersensitivity side effects have rarely included anaphylactic reaction, angioedema, laryngospasm, oropharyngeal spasm, pruritus, and urticaria.


Aripiprazole may be associated with orthostatic hypotension.

Collective data gathered from 17 placebo-controlled clinical studies (n=5106) involving the use of atypical antipsychotic agents, including aripiprazole (the active ingredient contained in Abilify) for the treatment of behavioral disorders in the elderly patient with dementia showed a risk of death 1.6 to 1.7 times greater in the drug-treated patient than in the placebo-treated patient. The average length of duration for the trials was 10 weeks with the cause of death in the majority of cases, though not all, reported as either cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature. Similar results (i.e., increased risk of mortality with atypical antipsychotics) were reported in another meta-analysis involving elderly dementia patients that consisted of 15 randomized, placebo-controlled trials (n=3353) of 10 to 12 weeks in duration. Aripiprazole is not approved by the FDA for use in the treatment of behavioral disorders in elderly patients with dementia.

An increased risk of mortality, possibly due to heart failure or sudden death, has been reported with the use of aripiprazole in the treatment of behavioral disorders in the elderly patient with dementia.

One case of dose-dependent incomplete right bundle-branch block has been reported following use of aripiprazole. Electrocardiographic findings returned to normal after discontinuation of aripiprazole.

A case of hypertensive crisis with tachycardia, confirmed upon rechallenge, has been reported following treatment with aripiprazole.

Cardiovascular side effects have frequently included hypertension (2%), hypotension, bradycardia, and both ventricular and supraventricular tachycardia. Palpitation, hemorrhage, heart failure, myocardial infarction, cardiac arrest, atrial fibrillation, AV block, prolonged QT interval, extrasystoles, myocardial ischemia, deep vein thrombosis, angina pectoris, pallor, cardiopulmonary arrest, cyanosis, and phlebitis have been reported infrequently. Bundle branch block, atrial flutter, vasovagal reaction, cardiomegaly, cardiomyopathy, thrombophlebitis, and cardiopulmonary failure have been reported rarely.


Possible risk factors for leukopenia/neutropenia include preexisting low white blood cell count (WBC) and history of drug-induced leukopenia/neutropenia. Patients with a history of a clinically significant low WBC or drug-induced leukopenia/neutropenia should have their complete blood count (CBC) monitored frequently during the first few months of therapy and discontinuation of aripiprazole (the active ingredient contained in Abilify) should be considered at the first sign of a clinically significant decline in WBC in the absence of other causative factors.
Patients with clinically significant neutropenia should be carefully monitored for fever or other symptoms or signs of infection and treated promptly if such symptoms or signs occur. Patients with severe neutropenia (absolute neutrophil count less than 1000/mm3) should discontinue aripiprazole and have their WBC followed until recovery.

Hematologic side effects have frequently included ecchymosis and anemia. Hypochromic anemia, leukocytosis, leukopenia, lymphadenopathy, eosinophilia, and macrocytic anemia have been reported infrequently. Thrombocythemia, thrombocytopenia, idiopathic thrombocytopenic purpura, and petechiae have been reported rarely. A reversible case of elevated triglyceride levels has also been reported.

In clinical trial and/or postmarketing experience, events of leukopenia/neutropenia have been reported temporally related to antipsychotic agents, including aripiprazole. Agranulocytosis has also been reported.


Metabolic side effects have frequently included weight loss, increased creatine phosphokinase, and dehydration. Edema, hyperglycemia, hypercholesterolemia, hypokalemia, diabetes mellitus, hypoglycemia, hyperlipemia, increased SGPT, thirst, increased BUN, hyponatremia, increased SGOT, increased creatinine, cyanosis, increased alkaline phosphatase, bilirubinemia, iron deficiency anemia, hyperkalemia, hyperuricemia, and obesity have been reported infrequently. Increased lactic dehydrogenase, hypernatremia, gout, and hypoglycemic reaction have been reported rarely.

Extreme cases of hyperglycemia associated with ketoacidosis, hyperosmolar coma, or death have been reported in patients treated with atypical antipsychotics. There have been few reports of hyperglycemia in patients treated with aripiprazole.

Although rare, aripiprazole-induced hyponatremia has been reported. In one case, hyponatremia developed two days after initiating therapy with aripiprazole 10 mg daily and resolved one week after discontinuation of treatment.


Psychiatric side effects have frequently included depression, schizophrenic reaction, hallucination, hostility, paranoid reaction, suicidal thought, manic reaction, delusions, and abnormal dream. Emotional lability, panic attack, manic depressive reaction, and visual hallucination have been reported infrequently. Obsessive thought and derealization have been reported rarely. In addition, at least one case of worsening psychosis has been associated with aripiprazole (the active ingredient contained in Abilify)

A possible worsening of preexisting schizoaffective disorder with the initiation of aripiprazole therapy has been reported.

Two cases of treatment-emergent psychosis and induction of mania have been reported in patients with schizoaffective disorder- bipolar type being switched to aripiprazole from high-potency dopamine receptor antagonists (i.e., perphenazine, fluphenazine). Symptoms resolved in both patients following discontinuation of aripiprazole.


Genitourinary side effects have frequently included vaginitis (6%), urinary tract infection (5%), and urinary incontinence. Urinary frequency, leukorrhea, urinary retention, cystitis, hematuria, dysuria, amenorrhea, vaginal hemorrhage, abnormal ejaculation, kidney failure, vaginal moniliasis, urinary urgency, gynecomastia, kidney calculus, albuminuria, breast pain, vaginal infection, vaginal mycosis, vaginal candidiasis, pyelonephritis, and urinary burning have been reported infrequently. Nocturia, polyuria, menorrhagia, anorgasmy, glycosuria, cervicitis, uterus hemorrhage, female lactation, urolithiasis, and priapism have been reported rarely.

One case of recurrent priapism associated with the use of aripiprazole has been reported. In this case, the first episode of priapism occurred within hours of the first dose of aripiprazole and following treatment for priapism the patient proceeded to have additional episodes of priapism over a period of 7 days even though no additional doses of aripiprazole were taken. The authors suggest that the recurrence of priapism over a week can be explained by aripiprazole's long half-life.


Hepatic side effects have rarely included hepatitis, hepatomegaly, cholecystitis, and cholelithiasis. Jaundice has been reported in postmarketing experience.


Endocrine side effects have infrequently included hypothyroidism. Goiter, hyperthyroidism, and hyperparathyroidism have been reported rarely.


In general, the incidence of side effects does not appear to be influenced by the age, gender, or race of the patient. Side effects associated with aripiprazole (the active ingredient contained in Abilify) are generally reported within the first week of therapy and resolve within 7 days.